President Obama signed a sweeping food safety bill into law today, marking the end of a lengthy legislative drama and turning the focus to whether the U.S. Food and Drug Administration will get the additional funding needed to implement the bill.

On the heels of a Tea Party-fueled midterm election, House Republicans have pledged to use their new majority to rein in federal spending and decrease the size of the bureaucracy–a tough environment for any government agency seeking greater resources.  Rep. Jack Kingston (R-GA), a fiscal conservative who will chair the subcommittee that oversees FDA’s budget, recently raised serious questions about the justification for the new food safety bill’s price tag.  The Congressional Budget Office estimates the new provisions will cost $1.4 billion over five years.

“I would not identify it as something that will necessarily be zeroed out, but it is quite possible it will be scaled back if it is significant overreach,” Kingston told the Washington Post in late December.  “We still have a food supply that’s 99.99 percent safe. No one wants anybody to get sick, and we should always strive to make sure food is safe. But the case for a $1.4 billion expenditure isn’t there.”

FDA Commissioner Margaret Hamburg told reporters on a White House media call Monday that she remains “optimistic” that the agency will be able to move forward and implement the bill, but declined to say whether the entire CBO estimate would be critical to carrying out all of the new responsibilities.  Those tasks include mandatory recall authority, increased inspection frequencies of high-risk facilities, and enforcing new requirements that growers and food facilities have food safety plans and that foreign facilities importing food to the U.S. must meet the same standards.

Shifting the federal food safety system, which haphazardly oversees a now global food system, from a reactive to a preventive system that enforces food safety regulations and inspects food facilities more than once a decade is no small feat.

“This is a major, historic piece of legislation … and it’s really Congress asking us to build a whole new system for food safety with all of the elements that you’ve been hearing about, some of those elements we’ve already been working on and will be able to put in place fairly quickly with existing resources.  Other components will require additional resources, dollar and human resources,” said Hamburg.   “We will be working closely with Congress and key stakeholders to try to really specify some of those needs.”

“Obviously the money that we have available in the annual budget cycle … ultimately impacts the way we are able to implement the bill,” said Hamburg, adding that FDA has been “very fortunate” to receive recent budget increases in recent years despite tough budgetary conditions.

When asked about Kingston’s comments about justifying the cost of implementing the bill,  Hamburg said that shifting the food safety system toward being preventive was “the appropriate way to go” and that the cost of not implementing the reforms would be “simply unacceptable.”

“We are very fortunate that we do have one of the safest food supplies in the world, however, every day we see preventable illness.   We see unnecessary hospitalization and too many people have died from foodborne disease that could have been prevented,” said Hamburg. “We are committed to taking on these new responsibilities and mandates given to us by Congress and we will work closely with Congress to implement this as efficiently and effectively as possible.”

Secretary of Health Kathleen Sebelius, also on the media briefing, called on Congress to fund the bill.