The Newest Damning Research on High Fructose Corn Syrup, and What it Means for Your Health



A new study published last week in the journal Obesity, found that popular sodas and other beverages sweetened with high-fructose corn syrup (HFCS) contain on average 18 percent more fructose than was previously thought.

Researchers from the University of Southern California tested beverages like Coke, Pepsi, and Sprite to determine the amount of fructose in each beverage. All of these beverages use HFCS as a sweetener, which is sweeter and cheaper than table sugar, or sucrose.

Sucrose is a disaccharide composed of half fructose and half glucose, while HFCS is composed of two monosaccharides, or separated fructose and glucose. Several studies had previously asserted that HFCS was essentially the same as table sugar, prompting some experts on nutrition to claim that there was no difference between the two biologically. New York University nutrition professor Marion Nestle was one of these high-profile experts, but after reading the new findings she was quick to admit her folly. She wrote last week on her blog, “I’ve been saying for ages that the sugar composition of high fructose corn syrup (HFCS) is no different from that of table sugar (sucrose). Oops.”

The New York Times also supported this notion by writing a recent editorial that stated,“In fact, when metabolized, high-fructose corn syrup is no different than sucrose—ordinary sugar made from cane or sugar beets.”

But according to these new findings, it turns out the differences are significant due to the higher percentage of fructose found in HFCS. The previous assumption was that HFCS was made up of 55 percent fructose—not substantially different than the 50 percent found in sucrose. However, the study found that Coke, Pepsi, and Sprite contained 65 percent fructose, and Dr. Pepper, Gatorade, and Arizona Ice Tea contained close to 60 percent fructose.

With the average American consuming about a gallon of soda a week, this amounts to exorbitant amounts of fructose. Add to this the HFCS found in a wide range of other packaged and processed foods, including fruit juice, soda, cereal, bread, yogurt, ketchup and mayonnaise, and the average American consumes 60 pounds of the sweetener every year.

A high intake of fructose is problematic for a number of reasons. Though both are simple sugars, fructose and glucose are metabolized differently. Glucose can be metabolized and burned efficiently for energy by cells and can also be stored in the liver or muscles as a carbohydrate (glycogen) for later use. Fructose, on the other hand, is metabolized in the liver rapidly and floods metabolic pathways leading to increased triglycerides and fat storage. Excessive fructose consumption can result in acute rise in blood pressure, insulin resistance and risk for diabetes, increased trigylceride serum levels leading to greater cardiovascular risk, non-alcoholic fatty liver disease, kidney stones, and weight gain.

One recent Princeton study found that rats drinking HFCS gained significantly more weight than rats drinking sugar water—even though the amount of calories consumed was the same. The rats drinking HFCS also exhibited signs of metabolic syndrome, including abnormal weight gain, especially visceral fat around the belly, and significant increases in circulating triglycerides. Male rats with access to HFCS gained 48 percent more weight than those eating a normal diet.

This study was completed in February, when it was assumed that the amount of fructose in HFCS was 55 percent. I shudder to think what the results would look like if the scientists did another study reflecting the discovery that the amount of fructose in the HFSC formulation is peaking at 65 percent.

This is yet another example of why avoiding processed foods is the best way to protect your health. Whatever scientists may say about the similarities between HFCS and table sugar, HFCS is not a whole food. The truth is that even table sugar is a highly refined product and is far from a whole food itself (despite the marketing of “natural sugar.”) Truly natural sugar comes in the form of fresh fruits and vegetables—and this should be where we get the bulk of the sugar in our diets. White sugar, along with HFCS are best avoided entirely.

I know this is not welcome news to many, so if you still need that sweet fix there are a few alternatives that when used in moderation present fewer problems on a metabolic level. Some of my favorites are: palm sugar, raw honey, organic maple syrup, and date sugar. But remember, these too are best used in moderation only—human beings are not equipped to eat large amounts of sweet foods (as the American diabetes epidemic attests to). Our hunter-gatherer ancestors, who we are biologically the same as, rarely encountered sweets in their lives. They ate fructose as it was found in nature—in fruits and vegetables, and on rare occasions some wild honey.

So while reducing your consumption of all sugars is really the best option, completely eliminating HFCS from your diet will go a long way in cutting back on your intake of fructose and with it the risk for a whole host of unpleasant health problems.

This article is part of a regular column by holistic nutrition expert Kristin Wartman, in which she examines food, nutrition, and the way the industrial food industry affects our food system and our health.

Photo: guytheorphan via flickr

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  1. Sunny
    Friday, November 5th, 2010
    What a crock of crap. It is the nature of sucrose that when it is mixed with water it seperates into glucose and fructose. When they make common table sugar from sugar cane or sugar beets it is combined with water as part of the refining process and in that form it is virtually identical to HFCS, i.e. it is made up of fructose and glucose. It is when the water is driven out that the two molecues combine making a disaccharide molecue. If you combine it with water either before or after you consume it then it becomes two molecues; one glucose and one fructose. It acts identically to HFCS. It isn't sweeter or less sweet then HFCS. If in making HFCS they continued the drying process the end product would be granular table sugar identical in every way with cane and beet sugar. The ONLY reason HFCS is left in liquid form is because it is ONLY used by food processors who prefer the liquid form as it is easier to transport and to mix with their product.
    You have HFCS derangement syndrome!
  2. Saturday, November 6th, 2010
    Not surprising. I used to consume vast quantities of Arizona Green Tea. I tried to call them at the 800 number on the gallon jug about ten times and finally just assumed they really didn't want to talk about it or change it, so, I quit, cold turkey. I miss it, but love my new drink. Filtered water at my sink!
  3. Saturday, November 6th, 2010
    I didn't read Sunny's response when I wrote mine, just the Wartman article. If what he or she says is true, then I am really amazed. In any case, consuming all that sugar is over for me and I feel much better!
  4. Antoine
    Sunday, November 7th, 2010
    I guess they call you "Sunny" 'cause you're so bright !!
  5. Sunny
    Wednesday, November 10th, 2010
    Your body runs on sugar. 100% of the carbohydrates you eat is converted to glucose and your body uses it for energy in your muscles, to keep your body warm and to think. You can avoid sucrose (table sugar) or HFCS (table sugar in a liquid form) but your body turns all the carbs into sugar. And if you don't eat enough carbs your body will turn fat and protein into sugar. It can even convert your own muscle tissue into sugar.
    If you notice that consuming sugar makes you hyper or sluggish or that avoiding sugar makes you feel much better then you have just succumbed to the nocebo effect. That is where you "think" you are reacting to something which will not cause a reaction. I hasten to add that if consuming sugar does give you physical symptoms then make an appointment with your doctor and get a FPG test because you may indeed have undiagnosed diabetes. But for the vast majority of us who do not have diabetes eating sugar will not make you hyper or slugish it merely fuels yur body.

    I choose "Sunny" because I feel good and I'm happy with life. I suppose if I didn't feel good and was unhappy I would have choosen "Gloomy".
  6. Ranjit. Patel
    Friday, June 16th, 2017
    Which soft drinks are free from fructose,eg Diet Coke, Sprite , lemonade etc
  7. William
    Wednesday, September 5th, 2018
    A grand-daughter had been diagnosed with stomach problems related to high fructose corn syrup. Parents are concerned with the methods of hiding fructose in many products, Is there any web site that wold be of further assistance to the parents.